Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 5/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981719 | 0.82 | ALDH1A1 (0.48) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL6978176 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL6981131 | 0.70 | CYP3A4 (0.56) | KDM4EALDH1A1HPGDMAPTHSD17B10 | |
| SCHEMBL5433434 | 0.69 | KDM4E (0.74) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL2179415 | 0.69 | MAPT (0.60) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL29099791 | 0.69 | KDM4E (0.74) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL29619913 | 0.69 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL2161251 | 0.69 | ALDH1A1 (1.00) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL394209 | 0.68 | MAOA (1.00) | KDM4EALDH1A1HPGDMAPTTSHR | |
| SCHEMBL6826170 | 0.68 | ALDH1A1 (0.64) | KDM4EALDH1A1HPGDMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105384-B1 | DIARYLBENZOPYRAN DERIVATIVES AS CYCLOOXYGENASE-2 INHIBITORS | PACIFIC CORP (KR) | 2003-03-26 | — | — | EP | disclosed |
| US-6340694-B1 | Diarylbenzopyran derivatives as cyclooxygenase-2 inhibitors | PACIFIC CORPORATION (KR) | 2002-01-22 | — | — | US | disclosed |