Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6960130 | 0.76 | ALDH1A1 (0.45) | RAB9AHTTERCC5FEN1HPGD | |
| Toluic Acid SCHEMBL551745 | 0.71 | ALDH1A1 (0.57) | NPC1RAB9AHTTERCC5FEN1 | |
| SCHEMBL7338845 | 0.70 | CA2 (0.43) | ERCC5FEN1HPGDL3MBTL1MAPK1 | |
| SCHEMBL10972155 | 0.66 | HPGD (0.50) | HTTERCC5FEN1HPGDALDH1A1 | |
| SCHEMBL778700 | 0.66 | HPGD (0.46) | NPC1RAB9AHTTERCC5FEN1 | |
| SCHEMBL29425530 | 0.66 | HPGD (0.54) | HTTERCC5FEN1HPGDALDH1A1 | |
| SCHEMBL29387256 | 0.66 | CYP3A4 (0.55) | HTTERCC5FEN1HPGDALDH1A1 | |
| SCHEMBL333141 | 0.66 | CYP3A4 (0.55) | HTTERCC5FEN1HPGDALDH1A1 | |
| SCHEMBL166603 | 0.66 | HPGD (0.54) | HTTERCC5FEN1HPGDALDH1A1 | |
| SCHEMBL8676355 | 0.66 | CA1 (0.47) | ERCC5FEN1L3MBTL1MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938483-B1 | MUSCARINIC ANTAGONISTS | SCHERING CORP (US) | 2003-02-26 | — | — | EP | disclosed |
| EP-0938483-A2 | MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998005292-A2 | PIPERIDINE AND PIPERAZINE DERIVATIVES AND THEIR USE AS MUSCARINIC ANTAGONISTS | SCHERING CORPORATION (US) | 1998-02-12 | — | — | WO | disclosed |