Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL509282 | 0.84 | TTR (0.42) | TTRALBALDH1A1CYP2A6VCAM1 | |
| SCHEMBL1401604 | 0.84 | VCAM1 (0.40) | TTRALBALDH1A1CYP2A6VCAM1 | |
| SCHEMBL10332556 | 0.76 | VCAM1 (0.35) | TTRALBVCAM1GPR35MEN1 | |
| SCHEMBL1708531 | 0.74 | VCAM1 (0.34) | TTRALBVCAM1GPR35MEN1 | |
| SCHEMBL4196636 | 0.71 | CYP2A6 (0.38) | TTRALBALDH1A1CYP2A6GPR35 | |
| SCHEMBL4190058 | 0.71 | TTR (0.33) | TTRALBALDH1A1CYP2A6MEN1 | |
| SCHEMBL1638135 | 0.71 | GPR35 (0.37) | TTRALBALDH1A1CYP2A6AR | |
| SCHEMBL491193 | 0.69 | — | — | |
| SCHEMBL220802 | 0.69 | — | — | |
| SCHEMBL1484862 | 0.67 | MAOA (0.46) | TTRALBALDH1A1CYP2A6VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423188-B1 | Intermediates in the preparation of agricultural/horticultural insecticides and method for using the same | MITSUI CHEMICALS AGRO INC (JP) | 2021-03-10 | — | — | EP | disclosed |
| EP-2334683-B1 | SATURATED BICYCLIC HETEROCYCLIC DERIVATIVES AS SMO ANTAGONISTS | MSD ITALIA SRL (IT) | 2017-03-22 | — | — | EP | disclosed |
| EP-1661886-B1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | MITSUI CHEMICALS AGRO INC (JP) | 2016-08-10 | — | — | EP | disclosed |
| US-9101135-B2 | Agricultural/horticultural insecticide and method for using the same | MITSUI CHEMICALS, INC. (JP) | 2015-08-11 | — | — | US | disclosed |
| US-9089133-B2 | Insecticide for agricultural or horticultural use and method of use thereof | MITSUI CHEMICALS, INC. (JP) | 2015-07-28 | — | — | US | disclosed |
| US-20140303377-A1 | AGRICULTURAL/HORTICULTURAL INSECTICIDE AND METHOD FOR USING THE SAME | MITSUI CHEMICALS, INC. (JP) | 2014-10-09 | — | — | US | disclosed |
| US-8816128-B2 | Insecticide for agricultural or horticultural use and method of use thereof | MITSUI CHEMICALS, INC. (JP) | 2014-08-26 | — | — | US | disclosed |
| US-8470823-B2 | Saturated bicyclic heterocyclic derivatives as SMO antagonists | INSTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.R.L. (IT) | 2013-06-25 | — | — | US | disclosed |
| US-20130066114-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2013-03-14 | — | — | US | disclosed |
| US-20120220802-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | MITSUI CHEMICALS, INC. (JP) | 2012-08-30 | — | — | US | disclosed |
| US-8158814-B2 | Insecticide for agricultural or horticultural use and method of use thereof | MITSUI CHEMICALS, INC. (JP) | 2012-04-17 | — | — | US | disclosed |
| EP-2423188-A1 | Agricultural/Horticultural Insecticide and Method for Using the Same | MITSUI CHEMICALS AGRO, INC. (JP) | 2012-02-29 | — | — | EP | disclosed |
| US-20110183989-A1 | SATURATED BICYCLIC HETEROCYCLIC DERIVATIVES AS SMO ANTAGONISTS | Instituto di Ricerche di Biologia Molecolare P. Ang | 2011-07-28 | — | — | US | disclosed |
| EP-2334683-A1 | SATURATED BICYCLIC HETEROCYCLIC DERIVATIVES AS SMO ANTAGONISTS | Istituto di ricerche di Biologia Molecolare P. Angeletti S.R.L. (IT) | 2011-06-22 | — | — | EP | disclosed |
| WO-2010023480-A1 | SATURATED BICYCLIC HETEROCYCLIC DERIVATIVES AS SMO ANTAGONISTS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P. ANGELETTI S.P.A. (IT) | 2010-03-04 | — | — | WO | disclosed |
| EP-2089384-A2 | 2-(PIPERIDIN-4-YL)-4-PHENOXY-OR PHENYLAMINO-PYRIMIDINE DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F. Hoffmann-Roche AG (CH) | 2009-08-19 | — | — | EP | disclosed |
| WO-2008071587-A2 | 2-(PIPERIDIN-4-YL)-4-PHENOXY- OR PHENYLAMINO-PYRIMIDINE DERIVATIVES AS NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-19 | — | — | WO | disclosed |
| US-20070027154-A1 | Insecticide for agricultural or horticultural use and method of use thereof | MITSUI CHEMICALS., INC. (JP) | 2007-02-01 | — | — | US | disclosed |
| EP-1661886-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | Mitsui Chemicals, Inc. (JP) | 2006-05-31 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140303377-A1 | AGRICULTURAL/HORTICULTURAL INSECTICIDE AND METHOD FOR USING THE SAME | CBR3, ATL3, CNPY2 | TTR 2421/4885ALB 2118/4885ALDH1A1 1956/4885 |
| US-20120220802-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | CYP1A2, CYP2C9, CYP3A7 | TTR 2848/4885ALB 1973/4885ALDH1A1 145/4885 |
| US-20130066114-A1 | INSECTICIDE FOR AGRICULTURAL OR HORTICULTURAL USE AND METHOD OF USE THEREOF | CYP2C8, CYP4F8, CYP3A7 | TTR 3076/4885ALB 2626/4885ALDH1A1 184/4885 |
| US-20070027154-A1 | Insecticide for agricultural or horticultural use and method of use thereof | CBR3, ATL3, CNPY2 | TTR 2231/4885ALB 2043/4885ALDH1A1 1149/4885 |
| US-20110183989-A1 | SATURATED BICYCLIC HETEROCYCLIC DERIVATIVES AS SMO ANTAGONISTS | SMO, SHH, GLI1 | TTR 4617/4885ALB 4861/4885ALDH1A1 1864/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.