Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972299 | 0.93 | TP53 (0.38) | TP53RAB9ALMNAMAPTCYP2D6 | |
| Trifluoroacetic Acid SCHEMBL9082506 | 0.89 | TP53 (0.34) | TP53RAB9ALMNAMAPTCYP2D6 | |
| SCHEMBL6964703 | 0.81 | RAB9A (0.36) | TP53RAB9ALMNAMAPTCYP2D6 | |
| SCHEMBL6980113 | 0.71 | CYP2D6 (0.33) | TP53RAB9ACYP2D6 | |
| Trifluoroacetic Acid SCHEMBL9082735 | 0.69 | EPHX1 (0.33) | — | |
| SCHEMBL6980426 | 0.66 | ALOX15 (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL6977270 | 0.65 | DPP7 (0.32) | — | |
| SCHEMBL6969922 | 0.63 | CYP2D6 (0.43) | TP53RAB9ALMNAMAPTCYP2D6 | |
| Trifluoroacetic Acid SCHEMBL6981240 | 0.63 | ALDH1A1 (0.41) | TP53RAB9A | |
| Trifluoroacetic Acid SCHEMBL6971868 | 0.63 | NISCH (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |