Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.73 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.73 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.73 |
| ▸ | MMP13 | P45452 | 9/20 | 0.68 |
| ▸ | ADAMTS4 | O75173 | 7/20 | 0.68 |
| ▸ | MMP9 | P14780 | 6/20 | 0.68 |
| ▸ | MMP2 | P08253 | 5/20 | 0.68 |
| ▸ | MMP3 | P08254 | 4/20 | 0.68 |
| ▸ | MMP1 | P03956 | 3/20 | 0.68 |
| ▸ | MMP7 | P09237 | 3/20 | 0.68 |
| ▸ | MMP12 | P39900 | 4/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8529829 | 1.00 | SLC1A3 (0.73) | SLC1A3SLC1A2SLC1A1MMP13ADAMTS4 | |
| SCHEMBL10052446 | 0.89 | MMP2 (0.78) | MMP13ADAMTS4MMP9MMP2MMP3 | |
| SCHEMBL3233597 | 0.87 | ADAMTS4 (0.68) | SLC1A3SLC1A2SLC1A1MMP13ADAMTS4 | |
| SCHEMBL7405654 | 0.87 | SLC1A3 (0.60) | SLC1A3SLC1A2SLC1A1MMP13ADAMTS4 | |
| SCHEMBL8742293 | 0.87 | SLC1A3 (0.67) | SLC1A3SLC1A2SLC1A1MMP13ADAMTS4 | |
| SCHEMBL1770811 | 0.86 | MMP1 (0.67) | SLC1A3SLC1A2SLC1A1MMP13MMP9 | |
| SCHEMBL12649188 | 0.86 | MMP1 (0.67) | SLC1A3SLC1A2SLC1A1MMP13MMP9 | |
| SCHEMBL10021355 | 0.86 | MMP9 (0.70) | SLC1A3SLC1A2SLC1A1MMP13ADAMTS4 | |
| SCHEMBL10830548 | 0.85 | ADAMTS4 (0.66) | SLC1A3SLC1A2SLC1A1MMP13ADAMTS4 | |
| SCHEMBL7322447 | 0.85 | ADAMTS4 (0.66) | SLC1A3SLC1A2SLC1A1MMP13ADAMTS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927716-B1 | Angiogenesis inhibitor | SENJU PHARMA CO (JP) | 2003-05-07 | — | — | EP | disclosed |
| US-6551999-B1 | For therapy and prophylaxis of angiogenesis associated with wound healing, inflammation, growth of tumor and the like; angiogenesis as seen in diabetic retinopathy, prematurity retinopathy, retinal venous occlusion, metastasis of tumors | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| EP-0928786-B1 | Angiogenesis inhibitor | SENJU PHARMA CO (JP) | 2003-01-02 | — | — | EP | disclosed |
| EP-0771565-B1 | Angiogenesis inhibitor | SENJU PHARMA CO (JP) | 2003-01-02 | — | — | EP | disclosed |
| US-6214800-B1 | ANGIOGENESIS INHIBITORS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2001-04-10 | — | — | US | disclosed |
| US-6057290-A | ADMINISTERING A CYSTEINE PROTEASE INHIBITOR TO A PATIENT FOR INHIBITING ANGIOGENESIS | SENJU PHARMACEUTICAL CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0928786-A1 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1999-07-14 | — | — | EP | disclosed |
| EP-0927716-A1 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |
| EP-0771565-A2 | Angiogenesis inhibitor | Senju Pharmaceutical Co., Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |
| US-5614522-A | SULFONAMIDE AND UREA-CONTAINING HYDROXYETHYLAMINE COMPOUNDS | G.D. SEARLE & CO. (US) | 1997-03-25 | — | — | US | disclosed |
| EP-0558673-B1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO CO (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0558673-A1 | RETROVIRAL PROTEASE INHIBITORS. | MONSANTO CO (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992008699-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| EP-0236164-B1 | DERIVATIVES OF N-ALPHA-ARYLSOLFONYLAMINOACYL P-AMIDINO-PHENYLALANINAMIDES, PROCESS FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND THEIR INTERMEDIATES | SANOFI (FR) | 1990-09-12 | — | — | EP | disclosed |
| EP-0236164-A1 | Derivatives of N-alpha-arylsolfonylaminoacyl p-amidino-phenylalaninamides, process for their preparation, their use as medicaments and their intermediates | SANOFI (FR) | 1987-09-09 | — | — | EP | disclosed |