Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973284 | 0.81 | CA1 (0.34) | KMT2ACNR1 | |
| SCHEMBL6974269 | 0.76 | CNR1 (0.41) | KMT2ACNR1 | |
| SCHEMBL6980056 | 0.71 | NOS3 (0.33) | CNR1 | |
| SCHEMBL6977981 | 0.65 | ALDH1A1 (0.41) | KMT2A | |
| SCHEMBL6979530 | 0.65 | SLC6A3 (0.39) | — | |
| SCHEMBL6978415 | 0.65 | CNR1 (0.41) | KMT2ACNR1 | |
| SCHEMBL6977300 | 0.62 | KMT2A (0.45) | KMT2ACNR1 | |
| SCHEMBL9195562 | 0.60 | TBXAS1 (0.34) | — | |
| SCHEMBL6969450 | 0.59 | MEN1 (0.38) | KMT2A | |
| SCHEMBL5197876 | 0.59 | ALDH1A1 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | disclosed |
| US-6011028-A | Cyclic amidino agents useful as nitric oxide synthase inhibitors | G.D. SEARLE & CO. (US) | 2000-01-04 | — | — | US | disclosed |
| EP-0821674-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1998-02-04 | — | — | EP | disclosed |
| WO-1996033175-A1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | G.D. SEARLE & CO. (US) | 1996-10-24 | — | — | WO | disclosed |