Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALKBH1 | Q13686 | 4/20 | 0.34 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.34 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7160276 | 0.84 | HSD11B1 (0.33) | — | |
| SCHEMBL6983648 | 0.84 | KMT2A (0.34) | SMN1; SMN2MAPTPKMKMT2AHPGD | |
| SCHEMBL6979923 | 0.78 | MALT1 (0.33) | — | |
| SCHEMBL10961245 | 0.77 | ALKBH1 (0.41) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL5883689 | 0.75 | ALKBH1 (0.51) | ALKBH1PRMT5WDR77PKMMEN1 | |
| SCHEMBL148140 | 0.74 | NPC1 (0.48) | SMN1; SMN2CYP2C9CYP2C19TDP1ALKBH1 | |
| SCHEMBL4701633 | 0.72 | HPGD (0.50) | SMN1; SMN2L3MBTL1MEN1KMT2AHPGD | |
| SCHEMBL17012297 | 0.71 | PRMT5 (0.42) | L3MBTL1ALKBH1PRMT5WDR77PKM | |
| SCHEMBL4700811 | 0.69 | ALKBH1 (0.31) | SMN1; SMN2L3MBTL1MAPTCYP2C9CYP2C19 | |
| SCHEMBL6979990 | 0.69 | MALT1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177194-B1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| US-6541423-B1 | Controlling vegatation | BASF AKTIENGESELLSCHAFT (DE) | 2003-04-01 | — | — | US | disclosed |