Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 11/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
| ▸ | PRKACB | P22694 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6977088 | 0.93 | CAMK2D (0.43) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6978549 | 0.90 | GSK3B (0.39) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6983727 | 0.89 | CAMK2D (0.44) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6982808 | 0.85 | CAMK2D (0.46) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6985258 | 0.85 | CAMK2D (0.39) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6977475 | 0.83 | CAMK2D (0.48) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6984540 | 0.82 | CAMK2D (0.46) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| Trifluoroacetic Acid SCHEMBL6981679 | 0.82 | GSK3B (0.38) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL7671215 | 0.81 | CAMK2D (0.49) | CAMK2DPIM1CCNT1CDK9CCNA2 | |
| SCHEMBL6981835 | 0.81 | CAMK2D (0.43) | CAMK2DPIM1CCNT1CDK9CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1095039-B1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 2003-08-27 | — | — | EP | disclosed |