Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | CD74 | P04233 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.51 |
| ▸ | PRKACA | P17612 | 1/20 | 0.51 |
| ▸ | NAMPT | P43490 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14133319 | 0.91 | ALDH1A1 (0.64) | KMT2AKDM4EARLOXL2LTA4H | |
| SCHEMBL3701935 | 0.84 | LTA4H (0.65) | KMT2AKDM4ELOXL2LTA4HMEN1 | |
| SCHEMBL12297165 | 0.84 | SREBF2 (0.62) | KMT2AKDM4ELOXL2LTA4HMEN1 | |
| SCHEMBL10610468 | 0.81 | HDAC1 (0.46) | KMT2AKDM4EARLOXL2LTA4H | |
| SCHEMBL10374749 | 0.81 | ALDH1A1 (0.50) | KMT2AKDM4EARLOXL2LTA4H | |
| SCHEMBL10373018 | 0.79 | CYP19A1 (0.47) | KMT2AKDM4ELOXL2LTA4HMEN1 | |
| SCHEMBL10952540 | 0.79 | CYP19A1 (0.53) | KMT2AKDM4EARMEN1ALDH1A1 | |
| SCHEMBL12890327 | 0.78 | ALDH1A1 (0.54) | KMT2AKDM4EARLOXL2LTA4H | |
| SCHEMBL10662640 | 0.78 | LOXL2 (0.55) | KMT2AKDM4EARLOXL2LTA4H | |
| SCHEMBL2315172 | 0.78 | HPGDS (0.53) | KMT2ALOXL2LTA4HMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828738-B1 | PYRIDYL-THIAZOLES AND THEIR USE TO PROTECT PLANTS AGAINST INFECTIONS BY MICRO-ORGANISMS | BAYER CROPSCIENCE AG (DE) | 2003-12-17 | — | — | EP | disclosed |
| EP-0169502-B1 | 2-BENZYL-4-(2-MORPHOLINO)-4-PYRIOL) THIAZOLE | MERCK & CO. INC. (US) | 1990-10-31 | — | — | EP | disclosed |
| US-4725606-A | AUTOIMMUNE DISEASES | MERCK & CO., INC. (US) | 1988-02-16 | — | — | US | disclosed |
| US-4725606-A | AUTOIMMUNE DISEASES | MERCK & CO., INC. (US) | 1988-02-16 | — | — | US | disclosed |
| US-4725606-A | AUTOIMMUNE DISEASES | MERCK & CO., INC. (US) | 1988-02-16 | — | — | US | disclosed |
| US-4697012-A | IMMUNOLOGY, ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1987-09-29 | — | — | US | disclosed |
| US-4697012-A | IMMUNOLOGY, ANTIINFLAMMATORY AGENTS | MERCK & CO., INC. (US) | 1987-09-29 | — | — | US | disclosed |
| EP-0169502-A3 | 2-BENZYL-4-(4-PYRIDYL)THIAZOLES AND DERIVATIVES THEREOF AS IMMUNOREGULANTS | — | 1987-02-25 | — | — | EP | disclosed |
| EP-0169502-A2 | 2-Benzyl-4-(2-morpholino)-4-Pyriol) Thiazole | MERCK & CO. INC. (US) | 1986-01-29 | — | — | EP | disclosed |