Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.38 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1397389 | 0.76 | DRD2 (0.60) | ALDH1A1MAPTKDM4ELMNADRD2 | |
| SCHEMBL14320628 | 0.76 | MAPT (0.59) | ALDH1A1MAPTKDM4ELMNADRD2 | |
| SCHEMBL6975324 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ELMNADRD2 | |
| SCHEMBL31346993 | 0.75 | MAPT (0.51) | ALDH1A1MAPTKDM4ELMNADRD2 | |
| Hydrochloric Acid SCHEMBL6345252 | 0.75 | KDM4E (0.59) | ALDH1A1MAPTKDM4ELMNADRD2 | |
| Hydrochloric Acid SCHEMBL6343779 | 0.75 | KDM4E (0.59) | ALDH1A1MAPTKDM4ELMNADRD2 | |
| SCHEMBL5701472 | 0.74 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4ELMNANR4A1 | |
| SCHEMBL24170260 | 0.73 | DRD2 (0.65) | ALDH1A1MAPTKDM4ELMNADRD2 | |
| SCHEMBL8984896 | 0.73 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4ELMNANR4A1 | |
| SCHEMBL10156824 | 0.72 | ALDH1A1 (0.48) | ALDH1A1MAPTKDM4ELMNADRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946539-B1 | SULPHONAMIDE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS MEDICAMENTS | SMITHKLINE BEECHAM PLC (GB) | 2003-08-13 | — | — | EP | disclosed |
| US-6599904-B2 | 5-HT6 receptor antagonists are believed to be of potential use in the treatment of certain CNS disorders; cognitive memory enhancement | SMITHKLINE BEECHAM P.L.C. (GB) | 2003-07-29 | — | — | US | disclosed |
| US-6423717-B1 | NERVOUS SYSTEM DISORDERS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-07-23 | — | — | US | disclosed |