Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 2/20 | 0.43 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | HTR3A | P46098 | 1/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | WHR1 | P49842 | 2/20 | 0.40 |
| ▸ | GAK | O14976 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31463572 | 0.90 | ALDH1A1 (0.41) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL10036161 | 0.88 | NR4A1 (0.50) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL26151424 | 0.82 | ALDH1A1 (0.36) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL26151702 | 0.82 | ADRB2 (0.36) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL14320628 | 0.82 | MAPT (0.59) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL10156824 | 0.81 | ALDH1A1 (0.48) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL5701472 | 0.81 | ALDH1A1 (0.57) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL1397389 | 0.80 | DRD2 (0.60) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL6979317 | 0.78 | MAPT (0.54) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL2779635 | 0.78 | HTR3E (0.68) | MAPTALDH1A1KDM4ELMNAHTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119899178-A | Aromatic amide derivative, preparation method thereof and application thereof in medicine | 浙江海正药业股份有限公司 | 2025-04-29 | — | — | CN | disclosed |
| WO-2024235073-A1 | AROMATIC AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE | 浙江海正药业股份有限公司 | 2024-11-21 | — | — | WO | disclosed |