Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.53 |
| ▸ | ACHE | P22303 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | CMA1 | P23946 | 1/20 | 0.41 |
| ▸ | PARL | Q9H300 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17643989 | 1.00 | MMP2 (0.53) | MMP2ACHEMEN1KMT2ACTSG | |
| SCHEMBL6981036 | 0.80 | MMP2 (0.54) | MMP2ACHEMEN1KMT2ACTSG | |
| SCHEMBL12808929 | 0.72 | MMP2 (0.54) | MMP2ACHEMEN1KMT2ACTSG | |
| SCHEMBL13998284 | 0.70 | ACHE (0.54) | MMP2ACHEMEN1KMT2ACTSG | |
| SCHEMBL5172912 | 0.70 | EPHX1 (0.48) | MMP2ACHEMEN1KMT2ACA12 | |
| SCHEMBL31173291 | 0.70 | ALDH1A1 (0.71) | MMP2ACHEKMT2ACTSGCMA1 | |
| SCHEMBL1792200 | 0.70 | ALDH1A1 (0.71) | MMP2ACHEKMT2ACTSGCMA1 | |
| SCHEMBL10851027 | 0.69 | ACHE (0.52) | MMP2ACHEKMT2ACTSGCMA1 | |
| SCHEMBL22308528 | 0.68 | ACHE (0.51) | MMP2ACHEPARLCA12CA2 | |
| SCHEMBL11973569 | 0.67 | MMP2 (0.59) | MMP2ACHECA2SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017161518-A1 | NEW PHYSICAL FORM | ASTRAZENECA AB (SE) | 2017-09-28 | — | — | WO | disclosed |