Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978879 | 0.88 | CTSK (0.50) | PRCPCTSKCCNKCDK12KDM4E | |
| SCHEMBL6976476 | 0.80 | F2 (0.36) | PRCP | |
| SCHEMBL6972556 | 0.80 | — | — | |
| SCHEMBL6970503 | 0.80 | PRCP (0.39) | PRCPCCNKCDK12KDM4EDPP7 | |
| SCHEMBL6976777 | 0.78 | MAOB (0.43) | — | |
| SCHEMBL6976622 | 0.77 | SMYD3 (0.41) | HTR2CHTR2BPLK1 | |
| SCHEMBL6976837 | 0.77 | F2 (0.37) | — | |
| SCHEMBL6976548 | 0.76 | MAOA (0.46) | KDM4EKMT2A | |
| SCHEMBL6975948 | 0.76 | F2 (0.39) | PRCPTERT | |
| SCHEMBL6979220 | 0.75 | NPC1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833839-B1 | PEPTIDYL HETEROCYCLES USEFUL IN THE TREATMENT OF THROMBIN RELATED DISORDERS | ORTHO PHARMA CORP (US) | 2003-01-08 | — | — | EP | claimed |