Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 8/20 | 0.33 |
| ▸ | RXRB | P28702 | 5/20 | 0.33 |
| ▸ | RXRG | P48443 | 4/20 | 0.33 |
| ▸ | RARB | P10826 | 5/20 | 0.32 |
| ▸ | RARG | P13631 | 5/20 | 0.32 |
| ▸ | RARA | P10276 | 4/20 | 0.32 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972568 | 0.88 | HDAC4 (0.31) | RXRAHDAC4 | |
| SCHEMBL8892644 | 0.76 | KDM4E (0.38) | RXRARARAHDAC4 | |
| SCHEMBL7675064 | 0.76 | CYP3A4 (0.36) | RXRARXRBRXRGHDAC4 | |
| SCHEMBL6982130 | 0.76 | RYR2 (0.32) | — | |
| SCHEMBL8892646 | 0.75 | LOX (0.33) | HDAC4 | |
| SCHEMBL7618967 | 0.75 | HDAC4 (0.33) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL6971025 | 0.71 | RARB (0.34) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7621921 | 0.70 | RXRA (0.39) | RXRARXRBRXRGRARBRARG | |
| SCHEMBL7816316 | 0.67 | MMP2 (0.31) | RXRA | |
| SCHEMBL7811190 | 0.66 | GAA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1080089-B1 | PYRAZOLYLDIOXOTHIOCHROMANOYL DERIVATIVES | BASF AG (DE) | 2003-11-05 | — | — | EP | disclosed |