Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | TERT | O14746 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8892646 | 0.85 | LOX (0.33) | LOXHDAC4 | |
| SCHEMBL6981388 | 0.80 | RXRA (0.38) | RARARXRARECQLMEN1PPARG | |
| SCHEMBL7675064 | 0.76 | CYP3A4 (0.36) | KDM4EALDH1A1HPGDRXRAHDAC4 | |
| SCHEMBL6972568 | 0.75 | HDAC4 (0.31) | RXRAHDAC4 | |
| SCHEMBL7617939 | 0.72 | SPR (0.33) | — | |
| SCHEMBL20921325 | 0.66 | LOX (0.41) | LOXHDAC4MEN1KMT2A | |
| SCHEMBL9770690 | 0.64 | ALDH1A1 (0.40) | KDM4EALDH1A1HPGDCYP1A2RARA | |
| SCHEMBL29829305 | 0.63 | CES2 (0.48) | KDM4EALDH1A1HPGDPOLBRECQL | |
| SCHEMBL2599798 | 0.60 | ALDH1A1 (0.33) | ALDH1A1LOX | |
| SCHEMBL12715259 | 0.59 | RXRA (0.38) | HPGDLOXRARARXRAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997019076-A1 | ISOXAZOLE-4-YL-BENZOYL DERIVATIVES AND THE USE THEREOF AS HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1997-05-29 | — | — | WO | disclosed |