Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
| ▸ | RELA | Q04206 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6306524 | 0.78 | GABBR2 (0.44) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL6976097 | 0.70 | MAPT (0.36) | ALDH1A1CA2CA9SMN1; SMN2CYP3A4 | |
| SCHEMBL19351217 | 0.67 | ACHE (0.43) | ALDH1A1L3MBTL1CA9SMN1; SMN2CYP3A4 | |
| SCHEMBL13955178 | 0.67 | GABBR2 (0.34) | CYP3A4HPGDMAPT | |
| SCHEMBL19351183 | 0.66 | TNKS2 (0.46) | CA1CA2CA9CYP3A4HPGD | |
| SCHEMBL13656879 | 0.65 | GABBR2 (0.44) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL7155129 | 0.65 | GABBR2 (0.44) | ALDH1A1NPC1PLA2G1BNFKB1CASP3 | |
| SCHEMBL13021639 | 0.64 | POLB (0.41) | ALDH1A1CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL10212113 | 0.64 | TP53 (0.39) | ALDH1A1CA1CA2CA9SMN1; SMN2 | |
| SCHEMBL1754083 | 0.64 | ACHE (0.54) | ALDH1A1L3MBTL1CA9SMN1; SMN2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159276-B1 | BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS | CIBA SC HOLDING AG (CH) | 2003-10-22 | — | — | EP | disclosed |