Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CD69 | Q07108 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18050475 | 0.80 | POLB (0.35) | ALDH1A1CA12CA9CA2ELANE | |
| SCHEMBL502464 | 0.79 | GABBR2 (0.43) | CA12CA9CA2ELANECD69 | |
| SCHEMBL29692994 | 0.79 | GABBR2 (0.43) | CA12CA9CA2ELANECD69 | |
| SCHEMBL8758597 | 0.72 | CYP3A4 (0.41) | MAPTALDH1A1SMN1; SMN2CA12CA9 | |
| SCHEMBL6313837 | 0.72 | CA2 (0.43) | ALDH1A1SMN1; SMN2CA12CA9CA2 | |
| SCHEMBL4140771 | 0.70 | CA12 (0.54) | MAPTALDH1A1CA12CA9CA2 | |
| SCHEMBL16134866 | 0.70 | CYP3A4 (0.62) | MAPTALDH1A1SMN1; SMN2CYP3A4LMNA | |
| SCHEMBL6981440 | 0.70 | ALDH1A1 (0.38) | MAPTALDH1A1SMN1; SMN2CA9CA2 | |
| SCHEMBL8758513 | 0.69 | CA12 (0.37) | MAPTALDH1A1SMN1; SMN2CA12CA9 | |
| SCHEMBL20094339 | 0.69 | TDP2 (0.37) | MAPTALDH1A1SMN1; SMN2ELANECD69 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159276-B1 | BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS | CIBA SC HOLDING AG (CH) | 2003-10-22 | — | — | EP | disclosed |
| EP-1159276-A2 | BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS | Ciba SC Holding AG (CH) | 2001-12-05 | — | — | EP | disclosed |
| WO-2000053597-A2 | BENZOFURAN-2-ONES AS COLORANTS FOR ORGANIC MATERIALS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2000-09-14 | — | — | WO | disclosed |