Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 5/20 | 0.52 |
| ▸ | ADRB2 | P07550 | 6/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 6/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978185 | 0.92 | ALDH1A1 (0.51) | NR3C1ADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL6981262 | 0.90 | NR3C1 (0.53) | NR3C1SMN1; SMN2ALDH1A1LMNAHPGD | |
| SCHEMBL6985425 | 0.89 | NR3C1 (0.52) | NR3C1ADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL6984844 | 0.83 | USP2 (0.39) | NR3C1ADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL6981558 | 0.82 | NR3C1 (0.37) | NR3C1ADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL6984052 | 0.82 | ADRB2 (0.48) | NR3C1ADRB2ADRB1ADRB3SMN1; SMN2 | |
| SCHEMBL6982740 | 0.81 | NR3C1 (0.59) | NR3C1SMN1; SMN2LMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6981078 | 0.81 | NR3C1 (0.58) | NR3C1SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL6981576 | 0.80 | NR3C1 (0.44) | NR3C1BRD4CREBBP | |
| Hydrochloric Acid SCHEMBL6980868 | 0.79 | NR3C1 (0.56) | NR3C1ADRB2ADRB1ADRB3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |