Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | IKBKB | O14920 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9454253 | 0.81 | CA12 (0.46) | ALDH1A1HDAC4HDAC6MAPTMEN1 | |
| SCHEMBL352449 | 0.81 | ALDH1A1 (0.49) | ALDH1A1MAPTNPC1RAB9AHTT | |
| SCHEMBL18506410 | 0.80 | CA12 (0.41) | ALDH1A1HDAC4HDAC6L3MBTL1MAPT | |
| SCHEMBL1800827 | 0.80 | HCAR2 (0.58) | ALDH1A1HDAC4HDAC6L3MBTL1MAPT | |
| SCHEMBL2184554 | 0.77 | GAA (0.44) | ALDH1A1HDAC4HDAC6MAPK1MAPT | |
| SCHEMBL368680 | 0.77 | ALDH1A1 (0.43) | ALDH1A1HDAC4HDAC6MAPTMEN1 | |
| SCHEMBL31124057 | 0.77 | MAPT (0.49) | ALDH1A1HDAC4HDAC6MAPTMEN1 | |
| SCHEMBL14770789 | 0.77 | RAB9A (0.45) | ALDH1A1HDAC4HDAC6MAPK1L3MBTL1 | |
| SCHEMBL21159080 | 0.77 | LMNA (0.43) | ALDH1A1HDAC4HDAC6L3MBTL1MAPT | |
| SCHEMBL2673666 | 0.76 | HDAC4 (0.39) | ALDH1A1HDAC4HDAC6L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761654-B1 | Isoxazole- and isothiazole-5-carboxamide derivatives, their preparation and their use as herbicides | BASF AG (DE) | 2003-06-18 | — | — | EP | disclosed |
| US-5780393-A | Herbicidal isoxazole and isothiazole-5-carboxamides | AMERICAN CYANAMID COMPANY (US) | 1998-07-14 | — | — | US | disclosed |
| EP-0761654-A1 | Isoxazole- and isothiazole-5-carboxamide derivatives, their preparation and their use as herbicides | American Cyanamid Company (US) | 1997-03-12 | — | — | EP | disclosed |