Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6968119 | 0.89 | — | — | |
| Trifluoroacetic Acid SCHEMBL6979873 | 0.86 | MEN1 (0.37) | — | |
| Trifluoroacetic Acid SCHEMBL6977922 | 0.82 | CYP1A2 (0.34) | — | |
| Trifluoroacetic Acid SCHEMBL6981240 | 0.78 | ALDH1A1 (0.41) | — | |
| SCHEMBL6969217 | 0.75 | SLC6A2 (0.36) | — | |
| Trifluoroacetic Acid SCHEMBL6978462 | 0.75 | MEN1 (0.39) | — | |
| Trifluoroacetic Acid SCHEMBL9082735 | 0.74 | EPHX1 (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL6979209 | 0.70 | DPP4 (0.43) | — | |
| Trifluoroacetic Acid SCHEMBL6969858 | 0.69 | CYP1A2 (0.31) | — | |
| SCHEMBL6964478 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |