Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MGAM | O43451 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SI | P14410 | 2/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6978023 | 0.90 | HTR2A (0.45) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| Trifluoroacetic Acid SCHEMBL6979873 | 0.83 | MEN1 (0.37) | MEN1KMT2AALDH1A1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL6981240 | 0.77 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6977300 | 0.77 | KMT2A (0.45) | MEN1KMT2AHTR2AHTR2CHTR2B | |
| Trifluoroacetic Acid SCHEMBL6977922 | 0.77 | CYP1A2 (0.34) | MAPT | |
| Trifluoroacetic Acid SCHEMBL6982053 | 0.75 | HTR5A (0.30) | — | |
| SCHEMBL6969217 | 0.72 | SLC6A2 (0.36) | MEN1KMT2AHTR2APKM | |
| Trifluoroacetic Acid SCHEMBL9082735 | 0.72 | EPHX1 (0.33) | ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6979209 | 0.70 | DPP4 (0.43) | ALDH1A1TDP1 | |
| Trifluoroacetic Acid SCHEMBL6973149 | 0.65 | DPP4 (0.36) | MAPK1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0821674-B1 | CYCLIC AMIDINO AGENTS USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | SEARLE & CO (US) | 2003-08-06 | — | — | EP | claimed |