Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.43 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 3/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980360 | 0.85 | SLC18A3 (0.40) | DRD2SLC18A3HTR7DRD4DRD3 | |
| SCHEMBL6985836 | 0.84 | DRD2 (0.40) | DRD2HTR7DRD4DRD3MEN1 | |
| SCHEMBL7811043 | 0.83 | DRD2 (0.43) | DRD2CARM1PRMT6SLC18A3HTR7 | |
| SCHEMBL6981562 | 0.83 | DRD2 (0.43) | DRD2CARM1PRMT6SLC18A3HTR7 | |
| SCHEMBL6981384 | 0.83 | DRD2 (0.43) | DRD2CARM1PRMT6SLC18A3HTR7 | |
| Hydrochloric Acid SCHEMBL6980227 | 0.83 | DRD2 (0.40) | DRD2HTR7DRD4DRD3MEN1 | |
| Hydrochloric Acid SCHEMBL6985847 | 0.82 | DRD2 (0.42) | DRD2CARM1PRMT6SLC18A3HTR7 | |
| Bromide SCHEMBL7811677 | 0.82 | DRD2 (0.42) | DRD2CARM1PRMT6SLC18A3HTR7 | |
| Hydrochloric Acid SCHEMBL7811763 | 0.82 | DRD2 (0.42) | DRD2CARM1PRMT6SLC18A3HTR7 | |
| Bromide SCHEMBL7811682 | 0.82 | DRD2 (0.42) | DRD2CARM1PRMT6SLC18A3HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |