Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 7/20 | 0.40 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | OGA | O60502 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 2/20 | 0.36 |
| ▸ | PRCP | P42785 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982079 | 0.85 | DRD2 (0.43) | SLC18A3DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL6983850 | 0.85 | MEN1 (0.39) | DRD2DRD3HTTHTR7 | |
| Hydrochloric Acid SCHEMBL6980238 | 0.84 | ALDH1A1 (0.40) | DRD2DRD3HTTHTR7 | |
| SCHEMBL7809132 | 0.81 | DRD2 (0.38) | SLC18A3DRD2DRD4DRD3SIGMAR1 | |
| SCHEMBL6981562 | 0.81 | DRD2 (0.43) | SLC18A3DRD2DRD4SIGMAR1HTR7 | |
| SCHEMBL7811043 | 0.81 | DRD2 (0.43) | SLC18A3DRD2DRD4SIGMAR1HTR7 | |
| SCHEMBL6981384 | 0.81 | DRD2 (0.43) | SLC18A3DRD2DRD4SIGMAR1HTR7 | |
| Fumaric Acid SCHEMBL9412812 | 0.80 | SLC18A3 (0.37) | SLC18A3DRD2DRD4DRD3SMN1; SMN2 | |
| Fumaric Acid SCHEMBL7802738 | 0.80 | SLC18A3 (0.37) | SLC18A3DRD2DRD4DRD3SMN1; SMN2 | |
| Fumaric Acid SCHEMBL7802740 | 0.80 | SLC18A3 (0.37) | SLC18A3DRD2DRD4DRD3SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923575-B1 | CYCLIC ETHER COMPOUNDS AS SODIUM CHANNEL MODULATORS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| US-6172085-B1 | CENTRAL NERVOUS SYSTEM AND PSYCHOLOGICAL DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-01-09 | — | — | US | disclosed |