Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 4/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.40 |
| ▸ | F2 | P00734 | 4/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | PLAT | P00750 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL7956640 | 0.99 | F10 (0.44) | F10NR3C1ALDH1A1LMNAHPGD | |
| SCHEMBL6982164 | 0.83 | F10 (0.44) | F10NR3C1ALDH1A1LMNANPSR1 | |
| Hydrochloric Acid SCHEMBL6977280 | 0.83 | NR3C1 (0.61) | F10NR3C1ALDH1A1LMNAHPGD | |
| Iodide SCHEMBL7964299 | 0.82 | PARP1 (0.39) | F10NR3C1ALDH1A1LMNAHPGD | |
| SCHEMBL6978677 | 0.80 | NR3C1 (0.40) | F10NR3C1ALDH1A1PLGF2 | |
| SCHEMBL7958935 | 0.80 | F10 (0.41) | F10NR3C1ALDH1A1HPGDPLG | |
| Hydrochloric Acid SCHEMBL6985449 | 0.79 | NR3C1 (0.40) | F10NR3C1ALDH1A1PLGF2 | |
| Iodide SCHEMBL7960088 | 0.79 | ALDH1A1 (0.41) | F10NR3C1ALDH1A1LMNAHPGD | |
| SCHEMBL6976365 | 0.79 | NR3C1 (0.45) | F10NR3C1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL7089726 | 0.79 | FFAR1 (0.47) | F10NR3C1ALDH1A1F2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |