Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.43 |
| ▸ | F2 | P00734 | 6/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982167 | 0.83 | F10 (0.44) | F10NR3C1F2PRSS1PDE4A | |
| Iodide SCHEMBL7956640 | 0.83 | F10 (0.44) | F10NR3C1F2PRSS1PDE4A | |
| Hydrochloric Acid SCHEMBL6977280 | 0.82 | NR3C1 (0.61) | F10NR3C1F2PRSS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7089726 | 0.81 | FFAR1 (0.47) | F10NR3C1F2PRSS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6985379 | 0.79 | ALDH1A1 (0.42) | F10NR3C1F2PRSS1ALDH1A1 | |
| SCHEMBL6981023 | 0.78 | RAB9A (0.45) | F10NR3C1F2PRSS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6981077 | 0.77 | RAB9A (0.44) | F10NR3C1F2PRSS1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6982225 | 0.77 | PARP1 (0.39) | F10NR3C1F2ALDH1A1GAA | |
| SCHEMBL6982740 | 0.76 | NR3C1 (0.59) | NR3C1F2LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6985423 | 0.76 | NR3C1 (0.44) | NR3C1ALDH1A1LMNAPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |