Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 6/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 6/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.40 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7080783 | 0.92 | POLB (0.48) | ITGB3ITGA2BPDK1PDK2PDK3 | |
| Hydrochloric Acid SCHEMBL6980241 | 0.91 | POLB (0.48) | ITGB3ITGA2BPDK1PDK2PDK3 | |
| SCHEMBL6984440 | 0.88 | F2 (0.44) | ITGB3ITGA2BPDK1PDK2PDK3 | |
| Hydrochloric Acid SCHEMBL6985575 | 0.87 | RXRA (0.48) | ITGB3ITGA2BMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7956609 | 0.87 | NR3C1 (0.44) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL6978012 | 0.85 | NR3C1 (0.49) | MAPTALDH1A1POLBTP53 | |
| SCHEMBL7948753 | 0.85 | ALDH1A1 (0.44) | ITGB3ITGA2BMAPTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL6982241 | 0.85 | NR3C1 (0.48) | MAPTALDH1A1POLBTP53 | |
| Hydrochloric Acid SCHEMBL6984887 | 0.84 | ALDH1A1 (0.43) | ITGB3ITGA2BMAPTSMN1; SMN2NPC1 | |
| SCHEMBL7958817 | 0.84 | NR3C1 (0.47) | MAPTALDH1A1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | claimed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | claimed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |