Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 5/20 | 0.39 |
| ▸ | ACHE | P22303 | 5/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4873666 | 0.78 | HTR2A (0.45) | BCHEACHEPOLBPGK1TSHR | |
| SCHEMBL6980148 | 0.77 | SMN1; SMN2 (0.43) | BCHEACHEPOLBALDH1A1KMT2A | |
| SCHEMBL6981458 | 0.77 | SMN1; SMN2 (0.43) | BCHEACHEPOLBALDH1A1KMT2A | |
| SCHEMBL6985684 | 0.75 | ADRA1B (0.47) | BCHEACHEL3MBTL1MAOB | |
| SCHEMBL6978015 | 0.72 | MEN1 (0.39) | BCHEACHEALDH1A1KMT2A | |
| SCHEMBL6987894 | 0.71 | ADRA1B (0.37) | BCHEACHEPOLBALDH1A1L3MBTL1 | |
| SCHEMBL6985013 | 0.70 | KMT2A (0.39) | POLBALDH1A1L3MBTL1KMT2AKDM4E | |
| SCHEMBL6987065 | 0.70 | POLB (0.39) | BCHEACHEPOLBALDH1A1L3MBTL1 | |
| SCHEMBL6979847 | 0.70 | ADRA1B (0.41) | BCHEACHEPOLBALDH1A1L3MBTL1 | |
| SCHEMBL6977033 | 0.70 | KMT2A (0.38) | BCHEACHEPOLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |