Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 3/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6981559 | 0.94 | ADRA1B (0.41) | ADRA1BL3MBTL1RCE1POLBBCHE | |
| SCHEMBL6987894 | 0.92 | ADRA1B (0.37) | ADRA1BL3MBTL1LMNAALDH1A1POLB | |
| SCHEMBL6985684 | 0.89 | ADRA1B (0.47) | ADRA1BL3MBTL1BCHEACHE | |
| SCHEMBL6985013 | 0.84 | KMT2A (0.39) | ADRA1BL3MBTL1ALDH1A1POLBKMT2A | |
| SCHEMBL6987065 | 0.84 | POLB (0.39) | ADRA1BL3MBTL1ALDH1A1RCE1POLB | |
| SCHEMBL6977033 | 0.83 | KMT2A (0.38) | ADRA1BL3MBTL1ALDH1A1POLBBCHE | |
| SCHEMBL6979427 | 0.81 | CYP2C19 (0.39) | ADRA1BL3MBTL1ALDH1A1RCE1POLB | |
| SCHEMBL6986602 | 0.80 | KDM4E (0.41) | L3MBTL1LMNAALDH1A1TSHRPOLB | |
| SCHEMBL4870329 | 0.80 | L3MBTL1 (0.40) | ADRA1BL3MBTL1LMNAALDH1A1THRB | |
| SCHEMBL6985645 | 0.80 | SLC6A2 (0.35) | ADRA1BLMNAALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289965-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-03-12 | — | — | EP | disclosed |
| WO-2001090081-A1 | SUBSTITUTED 1-AMINOALKYL-LACTAMS AND THEIR USE AS MUSCARINIC RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-29 | — | — | WO | disclosed |