Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 13/20 | 0.40 |
| ▸ | HTR6 | P50406 | 3/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL818662 | 0.92 | PLA2G2A (0.42) | PLA2G2AHTR6FABP4 | |
| SCHEMBL6970677 | 0.92 | PLA2G2A (0.39) | PLA2G2AHTR6 | |
| SCHEMBL29862814 | 0.86 | PLA2G2A (0.45) | PLA2G2AHTR6 | |
| SCHEMBL818540 | 0.86 | PLA2G2A (0.45) | PLA2G2AHTR6 | |
| SCHEMBL6978340 | 0.83 | PLA2G2A (0.41) | PLA2G2AHTR6 | |
| SCHEMBL8575155 | 0.81 | HTR6 (0.33) | HTR6FABP4 | |
| SCHEMBL6978338 | 0.79 | HTR6 (0.36) | HTR6FABP4 | |
| SCHEMBL6993129 | 0.78 | HTR6 (0.38) | HTR6FABP4 | |
| SCHEMBL3262705 | 0.77 | PLA2G2A (0.45) | PLA2G2AHTR6FABP4 | |
| SCHEMBL6993132 | 0.76 | FABP4 (0.35) | HTR6FABP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0839806-B1 | Substituted tricyclics | LILLY CO ELI (US) | 2003-07-09 | — | — | EP | disclosed |
| EP-0839806-A1 | Substituted tricyclics | ELI LILLY AND COMPANY (US) | 1998-05-06 | — | — | EP | disclosed |