Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983148 | 0.90 | ALDH1A1 (0.47) | KMT2AMEN1TSHRALDH1A1RAB9A | |
| SCHEMBL30261137 | 0.76 | ALDH1A1 (0.59) | KMT2AMEN1TSHRMAPK1ALDH1A1 | |
| SCHEMBL3992320 | 0.74 | KMT2A (0.56) | KMT2AMEN1TSHRMAPK1ALDH1A1 | |
| SCHEMBL3993901 | 0.72 | KMT2A (0.53) | KMT2AMEN1TSHRMAPK1ALDH1A1 | |
| SCHEMBL490752 | 0.71 | LDHA (0.57) | KMT2AMEN1TSHRALDH1A1POLB | |
| SCHEMBL6984542 | 0.71 | KMT2A (0.65) | KMT2AMEN1TSHRMAPK1ALDH1A1 | |
| SCHEMBL6699183 | 0.71 | PARP15 (0.54) | KMT2AMEN1ALDH1A1POLBNPC1 | |
| SCHEMBL23961118 | 0.69 | TSHR (0.53) | KMT2AMEN1TSHRMAPK1ALDH1A1 | |
| SCHEMBL25566925 | 0.69 | TSHR (0.53) | KMT2AMEN1TSHRMAPK1ALDH1A1 | |
| SCHEMBL27964009 | 0.69 | HSD17B10 (0.58) | KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345897-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002044150-A1 | CHEMICAL PROCESS AND NEW INTERMEDIATES | SANOFI-SYNTHELABO (FR) | 2002-06-06 | — | — | WO | disclosed |