Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.78 |
| ▸ | MEN1 | O00255 | 2/20 | 0.78 |
| ▸ | MAPT | P10636 | 2/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | GFER | P55789 | 1/20 | 0.78 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | ACHE | P22303 | 3/20 | 0.58 |
| ▸ | CHUK | O15111 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.55 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.54 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.52 |
| ▸ | MAP2 | P11137 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27174159 | 0.91 | MAPT (0.65) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL2597652 | 0.88 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29391519 | 0.88 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL9709251 | 0.82 | ABCG2 (0.68) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29453525 | 0.82 | CHUK (0.64) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL607827 | 0.82 | CHUK (0.64) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL22440894 | 0.81 | KDM4E (0.51) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29562964 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL29643258 | 0.79 | ALDH1A1 (1.00) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| Glycozoline SCHEMBL11981403 | 0.79 | ALDH1A1 (0.81) | ALDH1A1KDM4EMEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0985671-B1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARM CO LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| US-20020193369-A1 | Antifungal compounds and uses therefor | PROTEZ PHARMACEUTICALS INC. | 2002-12-19 | — | — | US | disclosed |
| WO-2002036203-A2 | AZOLE CONTAINING COMPOSITIONS WITH ENHANCED ANTIFUNGAL ACTIVITY | INFLUX, INC. (US) | 2002-05-10 | — | — | WO | disclosed |
| US-6197768-B1 | THERAPY, PREVENTION ISCHEMIC HEART DISEASE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2001-03-06 | — | — | US | disclosed |
| EP-0992240-A1 | THERAPEUTIC AGENT FOR ERECTION FAILURE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-12 | — | — | EP | disclosed |
| EP-0985671-A1 | PYRIDOCARBAZOLE DERIVATIVES HAVING cGMP-PDE INHIBITORY EFFECT | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-03-15 | — | — | EP | disclosed |
| US-6018046-A | SELECTIVE ACTION IN INHIBITING CYCLIC GMP-PHOSPHODIESTERASE (CGMP-PDE); PHARMACEUTICALS FOR TREATING DISEASES AGAINST WHICH THE INHIBITORY ACTION IS EFFECTIVE, SUCH AS PULMONARY HYPERTENSION | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 2000-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193369-A1 | Antifungal compounds and uses therefor | CYP51A1, ERG28, TPP1 | ALDH1A1 1449/4885KDM4E 2603/4885MEN1 435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.