Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.60 |
| ▸ | PARP1 | P09874 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31070742 | 0.86 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2APARP10LMNA | |
| SCHEMBL4812822 | 0.84 | LMNA (0.55) | ALDH1A1MEN1KMT2APARP10PARP1 | |
| SCHEMBL4810503 | 0.83 | ALDH1A1 (0.53) | ALDH1A1MEN1KMT2APARP1RAB9A | |
| SCHEMBL14879637 | 0.83 | HTT (0.68) | ALDH1A1MEN1KMT2APARP1RAB9A | |
| SCHEMBL27817675 | 0.81 | MEN1 (0.65) | ALDH1A1MEN1KMT2APARP10PARP1 | |
| SCHEMBL18171756 | 0.79 | ALDH1A1 (0.66) | ALDH1A1PARP10RAB9ALMNAKDM4E | |
| SCHEMBL28939142 | 0.78 | MAOB (0.63) | MEN1KMT2APARP1AKR1C1LMNA | |
| SCHEMBL718082 | 0.77 | PARP1 (0.79) | MEN1KMT2APARP10PARP1AKR1C1 | |
| SCHEMBL21545836 | 0.77 | KMT2A (0.59) | ALDH1A1MEN1KMT2APARP1RAB9A | |
| SCHEMBL27967403 | 0.76 | MAPT (0.58) | ALDH1A1MEN1KMT2APARP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020133004-A1 | Process for producing new oxazepine derivatives | AJINOMOTO CO. INC (JP) | 2002-09-19 | — | — | US | claimed |
| EP-1219611-A1 | NOVEL PROCESSES FOR PREPARING OXAZEPINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2002-07-03 | — | — | EP | claimed |
| EP-1219611-A4 | NOVEL PROCESSES FOR PREPARING OXAZEPINE DERIVATIVES | AJINOMOTO KK (JP) | 2003-03-19 | — | — | EP | disclosed |
| US-20020133004-A1 | Process for producing new oxazepine derivatives | AJINOMOTO CO. INC (JP) | 2002-09-19 | — | — | US | disclosed |
| US-20020133004-A1 | Process for producing new oxazepine derivatives | AJINOMOTO CO. INC (JP) | 2002-09-19 | — | — | US | disclosed |
| EP-1219611-A1 | NOVEL PROCESSES FOR PREPARING OXAZEPINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-1219611-A1 | NOVEL PROCESSES FOR PREPARING OXAZEPINE DERIVATIVES | Ajinomoto Co., Inc. (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001017980-A1 | NOVEL PROCESSES FOR PREPARING OXAZEPINE DERIVATIVES | AJINOMOTO CO., INC. (JP) | 2001-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020133004-A1 | Process for producing new oxazepine derivatives | KMO, CYP4B1, GRIN2B | ALDH1A1 391/4885MEN1 4577/4885KMT2A 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.