Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.46 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21042092 | 0.92 | ALDH1A1 (0.50) | KDM4EMAPTALDH1A1TDP1ALOX15 | |
| Hydrochloric Acid SCHEMBL28873434 | 0.90 | ALDH1A1 (0.49) | KDM4EMAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL45780 | 0.84 | KDM4E (0.68) | KDM4EMAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL3096482 | 0.79 | MAPT (0.73) | KDM4EMAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL30853462 | 0.78 | MAPT (0.62) | KDM4EMAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL4682191 | 0.78 | MAPT (0.62) | KDM4EMAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL6986243 | 0.77 | KDM4E (0.62) | KDM4EMAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL29673258 | 0.77 | KDM4E (1.00) | KDM4EMAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL45202 | 0.77 | KDM4E (1.00) | KDM4EMAPTALDH1A1TDP1ALOX15 | |
| SCHEMBL30011603 | 0.76 | KDM4E (0.73) | KDM4EMAPTALDH1A1TDP1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |