Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | RAF1 | P04049 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | CISD2 | Q8N5K1 | 1/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.34 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | ABCC9 | O60706 | 2/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 2/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6973224 | 0.86 | PPARA (0.43) | LMNAKMT2ANPSR1CYP1A2CYP2C19 | |
| SCHEMBL6979803 | 0.77 | PPARG (0.45) | KMT2AMAPTL3MBTL1PPARAALDH1A1 | |
| SCHEMBL6975862 | 0.77 | RAF1 (0.42) | LMNAKMT2ANPSR1RAF1POLB | |
| SCHEMBL6982722 | 0.74 | KEAP1 (0.45) | CYP1A2CYP2C19MAPTCYP2C9POLB | |
| SCHEMBL6971214 | 0.71 | PPARG (0.43) | KMT2AMAPTSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL6982573 | 0.71 | F10 (0.45) | LMNAKMT2AMAPTL3MBTL1GLA | |
| SCHEMBL6983394 | 0.71 | PPARG (0.44) | KMT2ANPSR1CYP1A2L3MBTL1PPARA | |
| SCHEMBL8715695 | 0.70 | ATM (0.42) | LMNAKMT2ACYP1A2CYP2C19MAPT | |
| SCHEMBL7372312 | 0.70 | KMT2A (0.47) | LMNAKMT2ANPSR1CYP1A2CYP2C19 | |
| SCHEMBL2172054 | 0.69 | AKR1C3 (0.48) | LMNAKMT2ANPSR1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1030835-B1 | UREA DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA UK LTD (GB) | 2003-01-22 | — | — | EP | disclosed |
| US-6344570-B1 | ANTISTICKING AGENTS FOR CELLS | ASTRAZENECA UK LIMITED (GB) | 2002-02-05 | — | — | US | disclosed |
| EP-1030835-A2 | UREA DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | AstraZeneca UK Limited (GB) | 2000-08-30 | — | — | EP | disclosed |
| WO-1999024398-A2 | UREA DERIVATIVES AND THEIR USE AS INTEGRIN INHIBITORS | ASTRAZENECA UK LIMITED (GB) | 1999-05-20 | — | — | WO | disclosed |