Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974883 | 0.85 | TP53 (0.41) | ALDH1A1SMN1; SMN2FFAR1MAPTMAPK1 | |
| SCHEMBL6984975 | 0.84 | DRD4 (0.57) | KCNJ1KCNH2DRD4ALDH1A1GAA | |
| SCHEMBL7956735 | 0.82 | KCNJ1 (0.51) | KCNJ1KCNH2DRD4ALDH1A1GAA | |
| SCHEMBL6980061 | 0.81 | KCNJ1 (0.47) | KCNJ1KCNH2DRD4ALDH1A1GAA | |
| SCHEMBL6983851 | 0.80 | KCNJ1 (0.39) | KCNJ1KCNH2ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL6984463 | 0.77 | POLB (0.44) | ALDH1A1LMNAKDM4E | |
| SCHEMBL6974890 | 0.74 | DPP8 (0.37) | KCNJ1KCNH2ALDH1A1SMN1; SMN2FFAR1 | |
| SCHEMBL24347338 | 0.71 | HSD17B3 (0.45) | ALDH1A1LMNAHPGD | |
| SCHEMBL6985351 | 0.69 | ALDH1A1 (0.54) | ALDH1A1TP53 | |
| SCHEMBL6975443 | 0.68 | TP53 (0.54) | ALDH1A1GAASMN1; SMN2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |