Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | YAP1 | P46937 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983851 | 0.85 | KCNJ1 (0.39) | DPP8DPP9FFAR1ALDH1A1L3MBTL1 | |
| SCHEMBL6979727 | 0.81 | TSHR (0.40) | DPP8DPP9FFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6974883 | 0.80 | TP53 (0.41) | FFAR1ALDH1A1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL6984466 | 0.80 | TDP1 (0.38) | DPP8DPP9ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL6977058 | 0.78 | FFAR1 (0.36) | DPP8DPP9FFAR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL6983845 | 0.74 | KCNJ1 (0.45) | FFAR1ALDH1A1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL6986713 | 0.71 | TSHR (0.41) | DPP8DPP9FFAR1ALDH1A1HPGD | |
| SCHEMBL6984463 | 0.71 | POLB (0.44) | ALDH1A1KDM4EKMT2A | |
| SCHEMBL6985353 | 0.71 | ALDH1A1 (0.46) | DPP8DPP9ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL7410532 | 0.69 | CHRM2 (0.41) | DPP8DPP9ALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |