Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ1 | P48048 | 2/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984975 | 0.94 | DRD4 (0.57) | KCNJ1KCNH2MAPTSMN1; SMN2DRD4 | |
| SCHEMBL7959087 | 0.84 | TP53 (0.48) | MAPTSMN1; SMN2ALDH1A1ABCB1GAA | |
| SCHEMBL6978707 | 0.82 | MAPT (0.58) | MAPTSMN1; SMN2ALDH1A1TP53HPGD | |
| SCHEMBL6983845 | 0.82 | KCNJ1 (0.45) | KCNJ1KCNH2MAPTSMN1; SMN2DRD4 | |
| SCHEMBL6979722 | 0.82 | TP53 (0.48) | MAPTSMN1; SMN2ALDH1A1TP53HPGD | |
| SCHEMBL6981640 | 0.80 | NR3C1 (0.47) | SMN1; SMN2ALDH1A1LMNATP53HPGD | |
| SCHEMBL6979462 | 0.80 | MAPT (0.58) | MAPTSMN1; SMN2DRD4ALDH1A1TP53 | |
| SCHEMBL6980061 | 0.80 | KCNJ1 (0.47) | KCNJ1KCNH2MAPTSMN1; SMN2DRD4 | |
| SCHEMBL6983746 | 0.80 | NR3C1 (0.47) | ALDH1A1LMNAGAAHPGDNPSR1 | |
| SCHEMBL6981826 | 0.80 | PDK1 (0.52) | ALDH1A1TP53HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6300342-B1 | FOR THERAPY OR INHIBITING THROMBUS FORMATION; FOR THERAPY OF FIBRIN-DEPENDENT INFLAMMATORY CONDITION | BOEHRINGER INGELHEIM PHARM KG (DE) | 2001-10-09 | — | — | US | disclosed |