SCHEMBL69840

SCHEMBL69840

CC1(C)c2cc(-c3cccc(B4OC(C)(C)C(C)(C)O4)c3)ccc2-c2ccc(-c3cccc(B4OC(C)(C)C(C)(C)O4)c3)cc21

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 10/20 0.50
LPL P06858 9/20 0.50
PGR P06401 4/20 0.35
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
DGAT1 O75907 1/20 0.34
IRAK4 Q9NWZ3 1/20 0.34
PDGFRB P09619 1/20 0.33
KDR P35968 1/20 0.33
PDK2 Q15119 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12127168 0.94 LIPG (0.49) LIPGLPLPDK2
SCHEMBL12177883 0.93 LIPG (0.48) LIPGLPLPDK2
SCHEMBL22989920 0.93 LIPG (0.48) LIPGLPLPDK2
SCHEMBL1753517 0.89 LIPG (0.50) LIPGLPLCA1CA2CA9
SCHEMBL15298702 0.89 LIPG (0.40) LIPGLPLPDK2
SCHEMBL29582631 0.89 PGR (0.44) LIPGLPLPGRPDK2
SCHEMBL18788582 0.89 PGR (0.44) LIPGLPLPGRPDK2
SCHEMBL429991 0.88 LIPG (0.64) LIPGLPLPGRCA1CA2
SCHEMBL24654450 0.88 LIPG (0.46) LIPGLPLDGAT1PDK2
SCHEMBL12781865 0.86 LIPG (0.56) LIPGLPLCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8129899-B1 Azafluorene derivative and organic light-emitting device using the derivative CANON KABUSHIKI KAISHA (JP) 2012-03-06 US disclosed
US-20120049176-A1 AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE CANON KABUSHIKI KAISHA (JP) 2012-03-01 US disclosed
US-8110685-B2 Efficient, durable electron transport layers; low driving voltage; simple, low cost production CANON KABUSHIKI KAISHA (JP) 2012-02-07 US disclosed
US-20080154040-A1 AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE CANON KABUSHIKI KAISHA (JP) 2008-06-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080154040-A1 AZAFLUORENE DERIVATIVE AND ORGANIC LIGHT-EMITTING DEVICE USING THE DERIVATIVE AZI2, CYP1A2, CYP2C19 LIPG 2246/4885LPL 2008/4885PGR 2453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.