SCHEMBL429991

SCHEMBL429991

CC1(C)c2cc(B3OC(C)(C)C(C)(C)O3)ccc2-c2ccc(-c3ccccc3)cc21

nearest known ligand 0.64

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
LIPG Q9Y5X9 11/20 0.64
LPL P06858 10/20 0.64
DGAT1 O75907 1/20 0.40
PDK2 Q15119 1/20 0.38
PDGFRB P09619 1/20 0.37
KDR P35968 1/20 0.37
P4HB P07237 1/20 0.36
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
KEAP1 Q14145 1/20 0.34
NFE2L2 Q16236 1/20 0.34
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34
BACE1 P56817 1/20 0.33
PGR P06401 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21693390 0.93 LIPG (0.59) LIPGLPLDGAT1PDK2PDGFRB
SCHEMBL12781865 0.93 LIPG (0.56) LIPGLPLDGAT1CA1CA2
SCHEMBL1753517 0.93 LIPG (0.50) LIPGLPLDGAT1CA1CA2
SCHEMBL15603770 0.92 LIPG (0.60) LIPGLPLDGAT1PDK2PDGFRB
SCHEMBL431646 0.91 LIPG (0.51) LIPGLPLDGAT1PDK2PDGFRB
SCHEMBL430244 0.91 LIPG (0.51) LIPGLPLDGAT1PDK2PDGFRB
SCHEMBL70387 0.90 LIPG (0.59) LIPGLPLDGAT1P4HBCA1
SCHEMBL1753909 0.89 LIPG (0.59) LIPGLPLDGAT1PDK2P4HB
SCHEMBL69840 0.88 LIPG (0.50) LIPGLPLDGAT1PDK2PDGFRB
SCHEMBL12056858 0.88 LIPG (0.70) LIPGLPLDGAT1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3037398-B1 METHOD FOR MANUFACTURING CHEMICAL COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-03-10 EP disclosed
WO-2020111663-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 두산솔루스 주식회사 2020-06-04 WO disclosed
WO-2020111663-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 두산솔루스 주식회사 2020-06-04 WO disclosed
US-9982087-B2 Method for producing compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-29 US disclosed
US-9982087-B2 Method for producing compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-05-29 US disclosed
EP-3225610-A1 METHOD FOR MANUFACTURING COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-10-04 EP disclosed
US-20160200861-A1 METHOD FOR PRODUCING COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-14 US disclosed
US-20160200861-A1 METHOD FOR PRODUCING COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-07-14 US disclosed
EP-3037398-A1 METHOD FOR MANUFACTURING CHEMICAL COMPOUND Sumitomo Chemical Company, Limited (JP) 2016-06-29 EP disclosed
US-8841004-B2 Binaphthyl compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2014-09-23 US disclosed
US-8841004-B2 Binaphthyl compound and organic light emitting element using the same CANON KABUSHIKI KAISHA (JP) 2014-09-23 US disclosed
US-20120061657-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-15 US disclosed
US-20120061657-A1 BINAPHTHYL COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT USING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-03-15 US disclosed
US-20110282063-A1 METHOD OF PRODUCING A DIAZAFLUORENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-11-17 US disclosed
US-20110282063-A1 METHOD OF PRODUCING A DIAZAFLUORENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2011-11-17 US disclosed
US-20080161574-A1 DIAZAFLUORENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-07-03 US disclosed
US-20080161574-A1 DIAZAFLUORENE COMPOUND CANON KABUSHIKI KAISHA (JP) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080161574-A1 DIAZAFLUORENE COMPOUND AFF1, NPFFR1, AFF2 LIPG 4352/4885LPL 4328/4885DGAT1 898/4885
US-20110282063-A1 METHOD OF PRODUCING A DIAZAFLUORENE COMPOUND AFF1, AFF2, AFF4 LIPG 4442/4885LPL 4158/4885DGAT1 913/4885
US-20160200861-A1 METHOD FOR PRODUCING COMPOUND NUDT1, OSGEP, CNOT9 LIPG 4765/4885LPL 4513/4885DGAT1 1134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.