Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 2/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.40 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.40 |
| ▸ | CLK2 | P49760 | 6/20 | 0.40 |
| ▸ | CLK3 | P49761 | 6/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6986226 | 0.91 | FLT3 (0.47) | PDE4BPDE7APTK2LRRK2MAP3K7 | |
| SCHEMBL6985231 | 0.84 | NPC1 (0.55) | NPC1RAB9ACYP3A4CYP2D6CYP2C9 | |
| SCHEMBL6981144 | 0.79 | CYP17A1 (0.50) | MAP3K7TAB1DYRK1ANPC1RAB9A | |
| SCHEMBL6985848 | 0.78 | DYRK1A (0.50) | MAP3K7TAB1DYRK1ACYP2E1CYP3A4 | |
| Hydrochloric Acid SCHEMBL6986821 | 0.78 | CYP17A1 (0.49) | MAP3K7TAB1DYRK1ANPC1RAB9A | |
| SCHEMBL6984794 | 0.78 | MKNK1 (0.44) | PTK2MAP3K7TAB1DYRK1ANPC1 | |
| SCHEMBL6987734 | 0.78 | MAP3K7 (0.40) | PDE4BPDE7APTK2MAP3K7TAB1 | |
| SCHEMBL6984271 | 0.77 | NPC1 (0.52) | MAP3K7TAB1DYRK1ANPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6982796 | 0.77 | MAP3K7 (0.40) | PDE4BPDE7APTK2MAP3K7TAB1 | |
| Hydrochloric Acid SCHEMBL6985178 | 0.77 | MKNK1 (0.43) | PTK2MAP3K7TAB1DYRK1ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | PDE4B 1968/4885PDE7A 1925/4885PTK2 4617/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.