Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | DYRK1A | Q13627 | 7/20 | 0.45 |
| ▸ | CLK2 | P49760 | 6/20 | 0.45 |
| ▸ | CLK3 | P49761 | 6/20 | 0.45 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.41 |
| ▸ | WNT1 | P04628 | 2/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 3/20 | 0.38 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.38 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984037 | 0.91 | PDE4B (0.43) | FLT3DYRK1ACLK2CLK3LRRK2 | |
| SCHEMBL6983318 | 0.85 | NPC1 (0.51) | BRAFMEN1NPC1RAB9AKMT2A | |
| SCHEMBL6985848 | 0.83 | DYRK1A (0.50) | DYRK1AMAP3K7TAB1MEN1 | |
| SCHEMBL6985095 | 0.80 | CYP11B1 (0.45) | DYRK1AMAP3K7TAB1NPC1RAB9A | |
| SCHEMBL6985509 | 0.80 | MKNK1 (0.46) | DYRK1ABRAFMAP3K7TAB1MEN1 | |
| SCHEMBL6981139 | 0.79 | CYP3A4 (0.54) | DYRK1AMAP3K7TAB1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6985047 | 0.79 | CYP11B1 (0.44) | DYRK1AMAP3K7TAB1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6979381 | 0.79 | MKNK1 (0.45) | DYRK1ABRAFMAP3K7TAB1MEN1 | |
| SCHEMBL6978941 | 0.78 | AXL (0.59) | DYRK1AMAP3K7TAB1MEN1 | |
| SCHEMBL6985821 | 0.78 | TDO2 (0.47) | DYRK1AMAP3K7TAB1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | FLT3 2678/4885DYRK1A 4799/4885CLK2 4601/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.