Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | BCR | P11274 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.46 |
| ▸ | ATR | Q13535 | 2/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.45 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983318 | 0.91 | NPC1 (0.51) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6984037 | 0.84 | PDE4B (0.43) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6978131 | 0.80 | MEN1 (0.51) | NPC1RAB9AALDH1A1CYP11B1CYP11B2 | |
| SCHEMBL6981771 | 0.78 | NPC1 (0.47) | NPC1RAB9AALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL6986460 | 0.78 | MKNK1 (0.46) | NPC1RAB9ASMN1; SMN2CYP11B1CYP11B2 | |
| SCHEMBL6981144 | 0.78 | CYP17A1 (0.50) | NPC1RAB9ASMN1; SMN2CYP11B1MAPT | |
| SCHEMBL6985848 | 0.77 | DYRK1A (0.50) | ALDH1A1CYP11B1CYP11B2PIK3CAPIK3CG | |
| Hydrochloric Acid SCHEMBL6986821 | 0.77 | CYP17A1 (0.49) | NPC1RAB9ASMN1; SMN2CYP11B1MAPT | |
| SCHEMBL6984271 | 0.76 | NPC1 (0.52) | NPC1RAB9AALDH1A1KDM4ETDP1 | |
| SCHEMBL6986226 | 0.75 | FLT3 (0.47) | NPC1RAB9AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | DAIICHI PHARMACEUTICAL CO. LTD. | 2003-07-10 | — | — | US | disclosed |
| EP-1283209-A1 | NOVEL BENZOTHIOPHENE DERIVATIVES | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2003-02-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130340-A1 | Novel benzothiophene derivatives | CYP17A1, CYP21A2, HSD17B1 | NPC1 693/4885RAB9A 4646/4885ALDH1A1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.