SCHEMBL6984069

SCHEMBL6984069

NC1(C(=O)O)CCN(C(=O)OCc2ccccc2)CC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.59
KMT2A Q03164 2/20 0.59
NPSR1 Q6W5P4 2/20 0.59
SMN1; SMN2 Q16637 3/20 0.59
CYP2C19 P33261 1/20 0.59
NPC1 O15118 3/20 0.58
RAB9A P51151 3/20 0.58
OPRD1 P41143 1/20 0.54
OPRK1 P41145 1/20 0.54
KDM1A O60341 2/20 0.51
ALDH1A1 P00352 2/20 0.50
ALOX15 P16050 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ENPP2 Q13822 1/20 0.49
ATXN2 Q99700 1/20 0.49
HDAC1 Q13547 3/20 0.48
HDAC6 Q9UBN7 3/20 0.48
HDAC3 O15379 2/20 0.48
HDAC2 Q92769 2/20 0.48
GRIN2B Q13224 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL29731215 0.99 MEN1 (0.58) MEN1KMT2ANPSR1SMN1; SMN2CYP2C19
SCHEMBL30057450 0.92 MEN1 (0.53) MEN1KMT2ANPSR1SMN1; SMN2CYP2C19
SCHEMBL9657187 0.87 SMN1; SMN2 (0.58) MEN1KMT2ANPSR1SMN1; SMN2CYP2C19
SCHEMBL1709936 0.86 MEN1 (0.59) MEN1KMT2ANPSR1SMN1; SMN2CYP2C19
SCHEMBL29266964 0.84 MEN1 (0.58) MEN1KMT2ANPSR1SMN1; SMN2CYP2C19
SCHEMBL56293 0.84 OPRD1 (0.58) MEN1KMT2ANPSR1SMN1; SMN2CYP2C19
SCHEMBL1709810 0.84 MEN1 (0.58) MEN1KMT2ANPSR1SMN1; SMN2CYP2C19
SCHEMBL6827246 0.84 MEN1 (0.61) MEN1KMT2ANPSR1SMN1; SMN2CYP2C19
SCHEMBL18132120 0.84 MEN1 (0.51) MEN1KMT2ANPSR1SMN1; SMN2CYP2C19
SCHEMBL934263 0.84 MEN1 (0.64) MEN1KMT2ANPSR1SMN1; SMN2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727543-A2 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A Plexium, Inc. (US) 2026-04-22 EP disclosed
WO-2024259345-A2 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT DEGRADE SWI/SNF-RELATED MATRIX-ASSOCIATED ACTIN-DEPENDENT REGULATOR OF CHROMATIN SUBFAMILY A Plexium, Inc. (US) 2024-12-19 WO disclosed
US-20240336612-A1 BRM Targeting Compounds And Associated Methods Of Use PRELUDE THERAPEUTICS INCORPORATED 2024-10-10 US disclosed
EP-4038052-B1 PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS DOMAIN THERAPEUTICS (FR) 2024-02-07 EP disclosed
WO-2023287787-A1 BRM TARGETING COMPOUNDS AND ASSOCIATED METHODS OF USE PRELUDE THERAPEUTICS, INCORPORATED (US) 2023-01-19 WO disclosed
WO-2021064189-A2 PROSTAGLANDIN E2 (PGE2) EP4 RECEPTOR ANTAGONISTS DOMAIN THERAPEUTICS (FR) 2021-04-08 WO disclosed
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE HURLEY TIMOTHY BRIAN 2009-08-13 US disclosed
EP-1119355-B1 NAPHTHALENECARBOXAMIDES AS TACHYKININ RECEPTOR ANTAGONISTS ASTRAZENECA AB (SE) 2003-01-08 EP disclosed
US-6500818-B1 Naphthalenecarboxamides as tachykinin receptor antagonists ASTRAZENECA AB (SE) 2002-12-31 US disclosed
CN-1322134-A Naphthalenecarboxamides as tachykinin receptor antagonists ASTRA ZENECA N V (SE) 2001-11-14 CN disclosed
EP-0231087-B1 HEPTANOYL-GLU-ASP-ALA-AMINO ACID IMMUNOSTIMULANTS PFIZER INC. (US) 1992-03-25 EP disclosed
US-4851388-A Heptanoyl-glu-asp-ala-amino acid immunostimulants PFIZER INC. (US) 1989-07-25 US disclosed
EP-0231087-A2 Heptanoyl-glu-asp-ala-amino acid immunostimulants PFIZER INC. (US) 1987-08-05 EP disclosed
WO-1987004440-A1 HEPTANOYL-GLU-ASP-ALA-AMINO ACID IMMUNOSTIMULANTS PFIZER INC. (US) 1987-07-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240336612-A1 BRM Targeting Compounds And Associated Methods Of Use ADRM1, BRDT, RBX1 MEN1 3067/4885KMT2A 1311/4885NPSR1 4135/4885
US-20090203694-A1 INHIBITORS OF UNDECAPRENYL PYROPHOSPHATE SYNTHASE FDPS, UMPS, GGPS1 MEN1 2345/4885KMT2A 4780/4885NPSR1 3199/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.