Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 5/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11341890 | 0.81 | CYP19A1 (0.49) | CYP19A1ARMAOBALDH1A1MAPT | |
| SCHEMBL11862421 | 0.78 | CYP19A1 (0.42) | CYP19A1ARDRD2DRD3MAPT | |
| SCHEMBL29903416 | 0.77 | MEN1 (0.49) | CYP19A1ARALDH1A1MAPTNPC1 | |
| SCHEMBL6436184 | 0.77 | MEN1 (0.49) | CYP19A1ARALDH1A1MAPTNPC1 | |
| SCHEMBL5451243 | 0.77 | MEN1 (0.49) | CYP19A1ARALDH1A1MAPTNPC1 | |
| SCHEMBL19423617 | 0.75 | FFAR1 (0.63) | CYP19A1FFAR1MAPTHSP90AA1 | |
| SCHEMBL11327485 | 0.74 | MAOB (0.44) | CYP19A1FFAR1MAOBALDH1A1MAPT | |
| SCHEMBL31357823 | 0.74 | ABCG2 (0.49) | CYP19A1ABCB1ARABCG2MAOB | |
| SCHEMBL11561473 | 0.73 | HTR1A (0.39) | CYP19A1DRD2DRD3MAPT | |
| SCHEMBL20439366 | 0.73 | MAOB (0.45) | CYP19A1FFAR1MAOBDRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620809-B2 | Useful in treating or in preventing melatoninergic disorders | LES LABORATOIRES SERVIER (FR) | 2003-09-16 | — | — | US | disclosed |
| EP-1106608-B1 | Substituted (dihydro)benzoxazine and (dihydro)benzothiazine derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2003-03-05 | — | — | EP | disclosed |
| US-20010003747-A1 | New substituted (dihydro)benzoxazine and (dihydro)benzothiazine compounds | LES LABORATOIRES SERVIER (FR) | 2001-06-14 | — | — | US | disclosed |
| EP-1106608-A1 | Substituted (dihydro)benzoxazine and (dihydro)benzothiazine derivatives, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 2001-06-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010003747-A1 | New substituted (dihydro)benzoxazine and (dihydro)benzothiazine compounds | MTNR1A, MTNR1B, SQOR | CYP19A1 277/4885FFAR1 1177/4885ABCB1 2686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.