Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.72 |
| ▸ | MAPT | P10636 | 5/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.72 |
| ▸ | GAA | P10253 | 3/20 | 0.72 |
| ▸ | MEN1 | O00255 | 3/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.72 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.60 |
| ▸ | NAMPT | P43490 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688602 | 0.91 | SMN1; SMN2 (0.57) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL6984178 | 0.88 | ALDH1A1 (0.59) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL7295990 | 0.88 | MAPT (0.58) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL21597667 | 0.86 | MEN1 (0.57) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL9023375 | 0.86 | SMN1; SMN2 (0.53) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL10941324 | 0.84 | NAMPT (0.69) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL23727080 | 0.84 | EPHX1 (0.62) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL8609963 | 0.84 | ALDH1A1 (0.51) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL28464045 | 0.84 | ALDH1A1 (1.00) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA | |
| SCHEMBL23727417 | 0.84 | EPHX1 (0.62) | ALDH1A1MAPTKMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040029875-A1 | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | LES LABORATOIRES SERVIER (FR) | 2004-02-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040029875-A1 | Novel aminotriazolone compounds, method for preparing same and pharmaceutical compositions containing same | ADORA1, AASDHPPT, AADAT | ALDH1A1 1009/4885MAPT 679/4885KMT2A 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.