Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | GLA | P06280 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3984394 | 0.82 | SMN1; SMN2 (0.42) | AKR1B1ALDH1A1KDM4ESMN1; SMN2GLA | |
| SCHEMBL18702830 | 0.81 | HSD17B10 (0.41) | AKR1B1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL4603472 | 0.81 | LIMK1 (0.44) | AKR1B1HSD17B10ATMKMT2AMAPT | |
| Hydrochloric Acid SCHEMBL4603416 | 0.79 | LIMK1 (0.43) | AKR1B1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8347082 | 0.77 | ALDH1A1 (0.35) | AKR1B1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL6981420 | 0.74 | LMNA (0.51) | ALDH1A1HPGDHTTSMN1; SMN2MEN1 | |
| SCHEMBL11877290 | 0.69 | GPR3 (0.40) | AKR1B1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL11085745 | 0.69 | MAOA (0.44) | ALDH1A1KDM4EHPGDHSD17B10MAPK1 | |
| SCHEMBL6985066 | 0.67 | AKR1B1 (0.59) | AKR1B1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL3805823 | 0.66 | GPR3 (0.42) | AKR1B1ALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274708-A1 | HERBICIDAL 3-HETEROCYCLIC SUBSTITUTED BENZISOTHIAZOLE AND BENZISOXAZOLE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001079203-A1 | HERBICIDAL 3-HETEROCYCLIC SUBSTITUTED BENZISOTHIAZOLE AND BENZISOXAZOLE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2001-10-25 | — | — | WO | disclosed |