Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | CUL4A | Q13619 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6982304 | 0.85 | KDM4E (0.39) | KDM4EMAPTKMT2AMEN1NPC1 | |
| SCHEMBL7158040 | 0.76 | CA12 (0.40) | KDM4EHPGDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL6184828 | 0.74 | CYP3A4 (0.46) | KDM4EHPGDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL6982298 | 0.70 | KDM4E (0.42) | KDM4EALDH1A1SMN1; SMN2MAPTKMT2A | |
| SCHEMBL8980273 | 0.70 | CA12 (0.47) | KDM4EALDH1A1MAPTHTTKMT2A | |
| SCHEMBL8980196 | 0.70 | KDM4E (0.35) | KDM4EHPGDALDH1A1NPC1RAB9A | |
| SCHEMBL984617 | 0.69 | NCEH1 (0.46) | KDM4EHPGDHSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL5544044 | 0.69 | ALDH1A1 (0.33) | KDM4EHSD17B10ALDH1A1HTTNPC1 | |
| SCHEMBL5544035 | 0.69 | ALDH1A1 (0.33) | KDM4EHSD17B10ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL7458773 | 0.68 | ALDH1A1 (0.35) | KDM4EHSD17B10ALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1177194-B1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AG (DE) | 2003-09-17 | — | — | EP | disclosed |
| EP-1177194-A1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-06 | — | — | EP | disclosed |
| WO-2000068228-A1 | 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-16 | — | — | WO | disclosed |