SCHEMBL6982298

SCHEMBL6982298

Cc1c(C(=O)O)ccc2scnc12

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.42
PKM P14618 1/20 0.42
XDH P47989 1/20 0.41
SLC22A12 Q96S37 1/20 0.41
TDP1 Q9NUW8 3/20 0.40
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
HKDC1 Q2TB90 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
EGLN1 Q9GZT9 1/20 0.38
DAO P14920 1/20 0.38
ALDH1A1 P00352 1/20 0.37
GABRP O00591 1/20 0.36
GABRD O14764 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRB1 P18505 1/20 0.36
GABRG2 P18507 1/20 0.36
GABRB3 P28472 1/20 0.36
GABRA5 P31644 1/20 0.36
GABRA3 P34903 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7158040 0.82 CA12 (0.40) KDM4ENPC1RAB9AL3MBTL1ALDH1A1
SCHEMBL27710065 0.78 XDH (0.40) KDM4EPKMXDHSLC22A12TDP1
SCHEMBL8980196 0.76 KDM4E (0.35) KDM4EPKMTDP1NPC1RAB9A
SCHEMBL6982304 0.76 KDM4E (0.39) KDM4EPKMTDP1NPC1RAB9A
SCHEMBL262049 0.75 ALDH1A1 (0.44) KDM4EXDHSLC22A12TDP1NPC1
SCHEMBL5544035 0.74 ALDH1A1 (0.33) KDM4EPKMTDP1NPC1RAB9A
SCHEMBL5544044 0.74 ALDH1A1 (0.33) KDM4EPKMXDHSLC22A12TDP1
SCHEMBL7458773 0.74 ALDH1A1 (0.35) KDM4ENPC1RAB9AALDH1A1SMN1; SMN2
SCHEMBL6979923 0.73 MALT1 (0.33) EGLN1
SCHEMBL28811371 0.73 XDH (0.48) KDM4EPKMXDHSLC22A12TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177194-B1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AG (DE) 2003-09-17 EP disclosed
US-6541423-B1 Controlling vegatation BASF AKTIENGESELLSCHAFT (DE) 2003-04-01 US disclosed
EP-1177194-A1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AKTIENGESELLSCHAFT (DE) 2002-02-06 EP disclosed
WO-2000068228-A1 4-(3',4'-HETEROCYCLYL BENZOYL) PYRAZOLES AS HERBICIDAL AGENTS BASF AKTIENGESELLSCHAFT (DE) 2000-11-16 WO disclosed
EP-0591786-B1 Photosensitive composition FUJI PHOTO FILM CO LTD (JP) 1996-05-15 EP disclosed
EP-0591786-A2 Photosensitive composition FUJI PHOTO FILM CO., LTD. (JP) 1994-04-13 EP disclosed