Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8316061 | 0.83 | CRY1 (0.35) | — | |
| SCHEMBL8318057 | 0.81 | KDM4E (0.39) | KDM4EPKML3MBTL1 | |
| SCHEMBL6982495 | 0.80 | KCNH2 (0.32) | — | |
| SCHEMBL8317165 | 0.74 | SLC6A2 (0.39) | KDM4EPKML3MBTL1 | |
| SCHEMBL8316696 | 0.73 | SLC6A2 (0.38) | KDM4EPKML3MBTL1 | |
| SCHEMBL6984197 | 0.72 | KDM4E (0.41) | KDM4E | |
| SCHEMBL6984303 | 0.72 | BRD4 (0.32) | HTR2C | |
| SCHEMBL7081764 | 0.72 | — | — | |
| SCHEMBL8317987 | 0.72 | ADRA2A (0.36) | KDM4EPKML3MBTL1 | |
| SCHEMBL8318169 | 0.70 | SLC6A2 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1131321-B1 | INDOLE DERIVATIVES AND THEIR USE AS SEROTONIN RECEPTOR LIGANDS | LILLY CO ELI (GB) | 2003-09-10 | — | — | EP | disclosed |
| US-6329366-B1 | HETEROCYCLIC, PIPERIDINE, INDOLE DERIVITIVES FOR TREATMENT OF NERVOUS SYSTEM DISORDERS AND SEROTONIN ANTAGONIST | ELI LILLY AND COMPANY LIMITED (GB) | 2001-12-11 | — | — | US | disclosed |