Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6984888 | 0.86 | MAPT (0.44) | HSD17B10MAPTMAPK1NPC1RAB9A | |
| SCHEMBL6981425 | 0.86 | F2 (0.41) | HSD17B10MAPTMAPK1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6981863 | 0.85 | F2 (0.41) | HSD17B10MAPTMAPK1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL7412062 | 0.82 | F2 (0.41) | HSD17B10MAPTMAPK1NPC1RAB9A | |
| SCHEMBL7411820 | 0.80 | AVPR2 (0.52) | MAPTMAPK1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6985072 | 0.78 | F2 (0.42) | HSD17B10MAPTMAPK1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6986049 | 0.78 | NR3C1 (0.60) | MAPTMAPK1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7080783 | 0.76 | POLB (0.48) | MAPTMAPK1NPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6979759 | 0.76 | PDK1 (0.51) | F2PLGPRSS1TPSAB1TPSD1 | |
| Hydrochloric Acid SCHEMBL6985503 | 0.76 | ITGB3 (0.43) | MAPTMAPK1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0991624-B1 | PHENYLALKYL DERIVATIVES WITH THROMBIN-INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-11-19 | — | — | EP | disclosed |